Immunizing for Acne? New Study Shows Promise
A new study from the University of California, San Diego may shine light on a new possible treatment for acne, vaccination. The idea of preventing acne with a vaccine is totally novel in the pantheon of treatments offered for this troubling condition. Generally acne is treated with a combination of methods, with everything from antibiotics, both topical and oral, to laser and light-based methods.
Doctors Nakatsuji et al of UCSD created an acne vaccine targeting a cell wall-anchored sialidase of P. acnes. The importance of sialidase to disease pathogenesis is shown by treatment of a human sebocyte cell line with recombinant sialidase that increased susceptibility to P. acnes cytotoxicity and adhesion. The researchers report:
